Expresión de búsqueda: RECEPTORS, KIR 
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Descriptor Inglés:   Receptors, KIR 
Descriptor Español:   Receptores KIR 
Descriptor Portugués:   Receptores KIR 
Sinónimos Inglés:   Killer Inhibitory Receptors
KIR Family Receptors
KIR Receptors  
Categoría:   D12.776.543.750.705.541
Definición Inglés:   A family of receptors found on NK CELLS that have specificity for a variety of HLA ANTIGENS. KIR receptors contain up to three different extracellular immunoglobulin-like domains referred to as D0, D1, and D2 and play an important role in blocking NK cell activation against cells expressing the appropriate HLA antigens thus preventing cell lysis. Although they are often referred to as being inhibitory receptors, a subset of KIR receptors may also play an activating role in NK cells. 
Nota de Indización Inglés:   general; prefer specifics
Nota Histórica Inglés:   2008(1997) 
Calificadores Permitidos Inglés:  
administration & dosage agonists
antagonists & inhibitors analysis
biosynthesis blood
chemistry classification
drug effects deficiency
genetics history
immunology isolation & purification
metabolism physiology
radiation effects therapeutic use
ultrastructure  
Número del Registro:   52815 
Identificador Único:   D054340 

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